Interline Therapeutics, a research firm focused on elucidating protein communities to define molecular mechanisms of disease, has announced it has raised $92m USD in funding. The money reportedly will be used to expand its research platform and to develop six of its key preclinical therapeutic programs.
Zach Sweeney, Interline Therapeutics CEO, recently spoke with Outsourcing-Pharma about the company’s work, its pursuit to find novel therapies for cancer and other conditions, and the future of drug discovery.
OSP: Who you are, specialties, and what sets you apart from companies offering similar solutions?
ZS: Interline Therapeutics is a drug discovery company founded to systematically define how protein communities (dynamic networks of interacting proteins) are dysregulated in disease. Our ultimate goal is to improve the process of discovering new medicines while developing new treatments for cancer and inflammatory diseases.
Drug development is more successful when it is based on targets validated by strong human genetic evidence, yet for many common diseases, the application of genetic information to drug discovery has met with limited success. We have enough data to know that many genetic variants cause disease by changing protein community dynamics, but the exact interactions and mechanisms are often still poorly defined.
New genetic technologies are now helping to elucidate protein communities known to contribute to disease, while advances in experimental and computational proteomics now enable the systematic characterization of protein communities in their native environments. These proteo-genomic data unlock new strategies for developing drugs for promising targets that were previously considered inaccessible.
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May 13, 2021 at 11:03PM
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Interline lands $92m to map, correct dysfunctional proteins - OutSourcing-Pharma.com
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